If your guide has broken and the element that you want to target is in the guide you can simply edit the guide, select the broken step and retarget the step by clicking on the element and saving the changes.

If the element you wanted to target wasn't in the guide, you will have to import a page with the element that you want to target in. Here's more information: http://help.nickelled.com/guides/add-a-missing-page-to-your-guide

And don't forget when creating a guide to take a snapshot by clicking 'Add next page' if the page is going to change.

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